Author(s): Eisay Ali Alkasak, Venkata Murali N and Sunita K

Abstract: Fish are important because they give both people and animals vital nutrients that improve growth and health. Unfortunately, overcrowding and environmental problems, such as poor water quality and other stressors, can cause disease outbreaks in farmed fish. Furthermore, multidrug resistance has grown to be a significant global public concern. Consequently, the use of immunostimulants rather than chemotherapeutic methods to manage disease in aquaculture is growing in significance. In such a scenario, screening for the impact of immunostimulants on the health of both healthy and pathogen-infected fish requires biomolecular evaluation. Catla Catla is a successfully cultivated freshwater species for consumption in India, owing to its significant nutritional and health benefits; however, there is a little information on the effect of immunostimulants on C. Catla. Therefore, in order to evaluate the impact of various immunostimulants on the biomolecular composition of both healthy and Aeromonas-infected C. Catla, the study sought to quantify biomolecules from muscle tissues. According to the results of this investigation, oral administration of a variety of immunostimulants, such as vitamin C, vitamin E, chitin, chitosan, and levamisole, significantly raised the levels of proteins, lipids, carbohydrates, free amino acids, reduced glutathione, and carotenoids in both healthy and Aeromonas-infected fish, thereby increasing tolerance against pathogenic infection. Furthermore, levamisole, vitamin C, and vitamin E demonstrated the highest efficacy among the immunostimulants that were examined. The results of this investigation showed that adding immunostimulants can greatly improve C. Catla growth, immunity, and survival rates.

DOI: 10.22271/fish.2025.v13.i6b.3183

Pages: 109-121  |  145 Views  71 Downloads

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