Author(s): Abiha Tarique, Zainab khatoon, Sunil P Trivedi and Vivek Kumar

Abstract: Environmental Protection includes programs that are aimed to reducing risks to the environment from hazardous materials and chemical wastes. Nowadays, 17α-ethinylestradiol, a synthetic estrogen, has become one of the most commonly used active ingredients for oral contraception, interfere with the normal functioning of endocrine systems, thus affecting reproduction and development in wildlife. The fresh water food fish, Channa punctatus, was selected as the test animal to perform the desired experimental work. The physio-chemical parameters (Temperature, pH, DO, CO2, and Hardness) of test medium, hematological (WBC, RBC, Hb, PCV, MCV, MCH, and Platelet) and biochemical (Total protein, AST, ALT, ALP, Urea and Creatinine) parameters of the fish were analysed. Channa punctatus was exposed to three different concentrations of 17α-ethinylestradiol (5, 10 and 20 ng/L), along with a control group for 28 days and their samples were collected at an interval of 7, 14, 21 and 28 days. Result shows that hematological parameters- RBC, Hb, PCV, MCV, MCH and Platelet were found significantly decreased and WBC significantly increased and the biochemical parameters- AST, ALT, ALP and Urea were found significantly increased while, Total protein and Creatinine showed insignificant differences on exposure to 17α-ethinylestradiol. Therefore, the study stated that 17α-ethinylestradiol produce an adverse effect in hematological and biochemical parameter which might affect normal physiology and immunity of fish.

DOI: 10.22271/fish.2023.v11.i3b.2814

Pages: 94-102  |  570 Views  347 Downloads

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