Author(s): Mehedi Mahmudul Hasan

Abstract: This study considered previously published sequences of VP19 and VP26 structural proteins of White Spot Syndrome Virus. The sequences were retrieved from National Center for Biotechnology Information (NCBI). VP 19 sequences were from the isolates of India, China, Singapore, Mexico and the Netherlands. VP26 sequences were from the isolates of India, China, Brazil and Mexico. These were aligned using UNIPROT and the phylogenetic trees were drawn through MEGA 7. VP19 sequence of the Singapore isolate (accession no. AAK96179) and VP26 sequence of the Chinese isolate were reference proteins in this study. Mutations were observed in the amino acid position of 9, 15, 66, 71, 73 and 95 in the VP19 sequences from other geographical locations than the reference one. In the VP26 sequences, mutations started from the 127^th amino acid position. Amino acid substitutions were observed in the hydrophobic, polar and charged regions of both the proteins. Although mutations were observed, the sequences of the individual proteins show a conserved nature in different geographical locations for the sequence homology.

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