Author(s): Dina Nath Pandit and Usha Rani

Abstract: This maiden study was designed to evaluate acute toxicity of tricyclazole and its responses on certain biomarker in a freshwater fish Channa punctatus (Bloch). By Reed-Muench method, mean 96hr-LC₅₀ dose of tricyclazole for this fish was calculated 25.0 mg l^-1. The LC₅₀ dose indicates highly toxic nature of tricyclaozole. Fish were then treated to 0.25 and 1.25 mg l^-1 sublethal dose of tricyclazole for short term long term exposure and the alterations in activities of glucose, protein, urea and cholesterol were determined in serum. Levels of glucose, urea and cholesterol in fish exposed to tricyclazole increased significantly (p<0.05) at all durations of short-term and long-term exposure. Conversely, protein decreased significantly (p<0.05) in response to tricyclazole at both the concentration and all exposure periods. Therefore, exposure to tricyclazole at sub-lethal concentrations induces severe serum biochemical alterations in Channa punctatus that may potentially disrupt their survival in their natural habitat. These findings may be used in the assessment of the potential risk of tricyclazole on food chain and aquatic ecosystems.

Pages: 246-250  |  694 Views  117 Downloads

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