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International Journal of Fisheries and Aquatic Studies
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P-ISSN: 2394-0506, E-ISSN: 2347-5129

International Journal of Fisheries and Aquatic Studies

2018, Vol. 6, Issue 4, Part A

Immune response in Channa punctatus after sub chronic 4-nonylphenol treatment and recovery


Author(s): Madhu Sharma, Pooja Chadha and Manoj Kumar Borah

Abstract: The effect of 4-nonylphenol (Surfactant) on blood parameter of fish Channa punctatus were evaluated after sub chronic exposure of 90 days and post treatment recovery was also ascertained by keeping fish in normal water for 30 days. The fish were exposed to different sub-lethal concentrations which were decided after calculating safe application rate for 90 days. Blood samples were collected after 30, 60 and 90 days respectively. Dose and time dependent effect of 4-NP was seen on differential leucocyte count (monocyte, lymphocyte and neutrophils). WBC differential count revealed a significant increase in the number of monocyte and neutrophils and decrease in the number of lymphocytes after 90 days of treatment. This can be considered as a clear evidence of altered immune system caused by 4-NP. On the other hand recovery indicates a considerable compensatory potential of C. punctatus immune system. This may be suggested parameter considered as useful biomarker for monitoring effect of toxicants in fish.

Pages: 20-23  |  743 Views  84 Downloads

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How to cite this article:
Madhu Sharma, Pooja Chadha, Manoj Kumar Borah. Immune response in Channa punctatus after sub chronic 4-nonylphenol treatment and recovery. Int J Fish Aquat Stud 2018;6(4):20-23.
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