Author(s): Madhu Sharma and Pooja Chadha

Abstract: Nonylphenol is the ultimate breakdown product of alkyphenol ethoxylate which is widely used in household and industrial products. As a result of widespread use and lipophilic nature there pervasiveness in the environment have been found everywhere. After that nonylphenol ethoxylates and their metabolites became a major focus of environmental research. Various studies have been performed regarding its endocrine disrupting effects, adverse developmental, reproductive, neurological effects on different organism which have been reviewed by various scientists. But the primary concern of the present review is the measurement of toxic effect of 4-nonylphenol (4-NP) ultimate degradation product of nonylphenol ethoxylates in different organism. Review is limited to, the studies related to genotoxicity, haemotoxicity and histopathological alterations in effect to 4-NP. This review provides evidence for environmental endocrine disruption and sequelae on genotoxic, haemotoxic and histopathological effects, as well as its status in India regarding its concentration in river water and research status.

Pages: 190-197  |  1203 Views  275 Downloads

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