Author(s): Sunaina and B Alam Ansari

Abstract: Heavy metals are natural trace components of the aquatic environment, but their levels have elevated due to domestic, industrial, mining and other activities. These heavy metal toxicant are accumulated in the fish through general body, they damage and weaken the mechanism concerned leading to physiological, pathological and biochemical disorders. High concentration of metals can however cause cellular and histological changes. Copper is an essential element for living organisms. Presence of copper in fresh water in higher concentration is toxic to organisms of experimental fishes (Zebrafish) liver and ovary. Zebrafish were exposed to different concentrations (20% and 80% of 96 hour LC₅₀) of copper. Reduction in CAT and GSH observed whereas LPO was elevated. CAT activity in liver for 7 days 20% is 93% while it decreased at 28 days is 65%. GSH level of 7 days in liver is 90% while much reduction was observed at 28 days is 56%. After 7 days treatment of LPO at 20% increased to 110% and more reduction was observed at 28 days is 136% at 80%. Values are significant at P<0.05.

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