Author(s): KP Asifa and KC Chitra

Abstract: The present study was undertaken in order to evaluate the induction of oxidative stress by the exposure to nonylphenol in testis of cichlid fish, Etroplus maculatus. Nonylphenol at one-fifth (178 μg/ L) and one-tenth (89 μg/ L) of LC₅₀ concentrations were exposed to fishes for 24, 72 and 96 h. Analysis of various antioxidant enzymes as superoxide dismutase, catalase and glutathione reductase were measured in the crude homogenate of testis. The levels of hydrogen peroxide generation and lipid peroxidation were also tested at both concentrations in all treatment groups. The results pointed out that nonylphenol treatment caused significant (P<0.05) decrease in the activities of antioxidant enzymes with concomitant significant (P<0.05) increase in the levels of hydrogen peroxide generation and lipid peroxidation in concentration-dependant and time-dependant manner. Therefore, the present study reveals that nonylphenol exposure increased reactive oxygen species production in testicular cells that could potentially resulted in enhanced oxidative stress.

Pages: 453-456  |  1444 Views  74 Downloads

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