Author(s): Neelima P, Govinda Rao K, Gopala Rao N, Chandra Sekhara Rao Jammu

Abstract: An attempt has been made to assess the acute toxic effect of Cypermethrin (25%EC) on LDH, GDH and AChE in different tissues of Cyprinus carpio. Fishes were exposed to sub lethal concentrations (5, 10, 15 and 20 per cent of 96h LC50 value) of cypermethrin for three different exposure periods, 5, 10 and 15 days. Activity levels of LDH, GDH were found to increase in all the tissues of the fish. Maximum percentage of elevation in LDH activity was (74.29%) in liver and minimum elevation was (19.74%) in kidney at 15 days and 15% 96h LC50. Initial increase was decreased in all the tissues studied at 20% 96h LC50 at all the exposure periods. Maximum percentage of elevation in GDH activity was (23.95%) in liver and minimum elevation was (19.04%) in kidney 15 days and 15% 96h LC50. Increase was decreased in all the tissues studied at 20% 96h LC50 at all the exposure periods. Activity levels of AChE were found to decrease in all the tissues. Maximum percentage of decrement in AChE activity was (25.55%) in brain and minimum was (23.94%) in kidney at the longest exposure period and highest sublethal concentration. Dose and exposure period dependant alterations were observed which were statistically significant.

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