Author(s): Leena muralidharan

Abstract: The effect of chronic exposure to a sublethal concentration of the fenthion pesticide, on enzyme activities in liver, brain, and muscles of the freshwater teleost fish, Cyprinus carpio, was studied after period of two months. The comparative study between control and the exposed fish revealed that there was a slight difference in enzyme activity at the lowest concentration while severe inhibition of all enzymes activity were observed at the concentrations, 0.38 and 0.193 mg/1. Among the three concentrations selected, the highest concentration seems to be the most highly potent and cause significant change in enzyme activity. The inhibitory effect on LDH and SDH activity of C. carpio is dependent on the concentration of insecticide during 60 days exposure test period The activity of GOT and GPT decreased significantly in both, the muscle and liver of Fenthion exposed fish C. carpio. There was a decrease in acid and alkaline phosphatase activity in muscle and liver of Fenthion treated fish C. carpio Adenosine triphosphatase activity was reduced in both liver and muscle tissues of exposed fish C. carpio. The inhibition of AChE was remarkable in all the experimentally exposed fishes depending upon the concentration of Fenthion and exposure period. The results suggest that anaerobic metabolism was favoured and aerobic oxidation of pyruvate was impaired in fish exposed to fenthion.

Pages: 51-56  |  1291 Views  106 Downloads

Download Full Article: Click Here