Contact: +91-9711224068
International Journal of Fisheries and Aquatic Studies
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal

(ICV-Poland) Impact Value: 76.37, Impact Factor: RJIF 5.69
E-ISSN: 2347-5129, P-ISSN: 2394-0506

International Journal of Fisheries and Aquatic Studies

2017, Vol. 5, Issue 2, Part I

Biological activities of some marine sponge extracts from Aqaba Gulf, Red Sea, Egypt


Author(s): El-Damhougy KA, Hussein A El-Naggar, Hassan AH Ibrahim, Mansour AE Bashar and Fekry M Abou Senna

Abstract: Two marine sponge species (Grayella cyathophora and Negombata magnifica) were collected during winter 2016 from Gulf of Aqaba, Red Sea, Egypt. The sponge samples were investigated as a promising source of natural products which can be used as antitumor, antiviral, antimicrobial, antioxidant, and anti-inflammatory agents. The present results revealed that the crude extract of G. cyathophora showed the high cytotoxic effect to Vero cell with hepatitis A virus which exhibits that Minimum inhibitor concentration was 2.929µg/ml. Also, it showed positive antibacterial activity against P. aeruginosa and the antioxidant activity compared to standard ascorbic acid was very weak with a value of 748μg / mL as IC50 and the activity of this anti-inflammatory extract was also (89.91%).At the same time, the crude extract of N. magnifica showed high antitumor activity with value of 1.09µg/ml and 0.37 µg/ml as IC50 against colon cancer (caco-2) and breast cancer (Mcf-7) on cell line, respectively, it does not possess any effect as an antiviral, antibacterial, anti-inflammatory and antioxidant activities. Generally, the present results confirmed that the ethanolic crude extract of N. magnifica conducted to promising antitumor agent and that of G. cyathophora conducted to promising anti-inflammatory and antiviral agents.

Pages: 652-659  |  471 Views  22 Downloads

Download Full Article: Click Here

How to cite this article:
El-Damhougy KA, Hussein A El-Naggar, Hassan AH Ibrahim, Mansour AE Bashar and Fekry M Abou Senna. Biological activities of some marine sponge extracts from Aqaba Gulf, Red Sea, Egypt. International Journal of Fisheries and Aquatic Studies. 2017; 5(2): 652-659.
ADVERTISEMENT
Mosquito Journal
Call for book chapter
Journals List Click Here Research Journals Research Journals